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• Multidrug Resistance Mutation (MDR1)

  Many herding breeds (most commonly Collies and Australian Shepherds) have a mutation at the MDR1 gene that makes them more sensitive to the negative effects of certain medications. These drugs include several antiparasitic agents (when given at high doses), the antidiarrheal agent loperamide (Imodium®), and several anticancer drugs. The effects of the mutation vary in severity, depending on whether the dog carries one or two copies of the mutation. There is a cheek swab or a commercially-available test that assesses blood samples for the presence of the MDR1 mutation.

• Muscle Tears in Dogs

  Muscle tears are direct or indirect traumatic injuries that cause damage to muscle tissue. The most common cause is an indirect injury, or strain, caused by overstretching during athletic activities, such as running or jumping. This handout discusses muscle tears in dogs and reviews the causes of these injuries, the clinical signs, diagnostic testing, therapy, and expected prognosis.

• Muscular Dystrophy

  This handout discusses muscular dystrophy (MD), primarily in dogs. The cause of the disease is a defect in the proteins found in muscle cells. It is often an inherited disease, usually affecting young dogs. Clinical signs (usually starting as muscle weakness) and diagnosis of the condition are outlined. There is no effective treatment for the condition.

• Mushroom Toxicity

  Mushroom toxicity can run the gamut from irritating illness to severe toxicity to death. The species of mushroom and amount ingested determine the severity of the toxicity. Since mushrooms are difficult to identify, it is best to discourage your pet from eating any mushrooms growing in the wild. In the event of mushroom ingestion, prompt treatment is critical to successful treatment. Pet owners need to be alert to the possibility of mushroom toxicity and work to eliminate their pet’s access to mushrooms.

• My Dog Won’t Eat: Feeding Picky Eaters

  Picky eaters are often created by their humans offering too much variety of food. It is safe for an otherwise healthy dog to not eat for up to a week. To decrease pickiness, having food available for only 15-30 minutes 2-3 times a day can be beneficial. Human food should not be used as a diet as it will lead to nutrient deficiencies. Certain foods are okay to mix with dog food to make them more appealing but check with your veterinarian before including these in your dog’s diet. Many dogs are not programmed to eat every day.

• Nasal Tumors

  Nasal tumors are an uncommon type of cancer but when they do occur, they tend to be malignant and locally aggressive. Staging can be done to determine the type of cancer and if it has affected anywhere else in the body. Treatment can be done in some cases to help relieve clinical signs, most often with radiation therapy.

• Neapolitan Mastiff

  True to his heritage and looks, the Neapolitan Mastiff can be a tough character. He's suspicious of strangers, aloof with acquaintances, but fiercely loyal to family. He's generally laid-back at home, and he doesn't bark a lot. Of course, when he does, you'll hear it.

• Neuroendocrine Tumors

  Neuroendocrine tumors are a group of tumors that develop from the cells of the neuroendocrine system, and include insulinomas, gastrinomas, glucagonomas, carcinoids, medullary thyroid carcinomas, small-cell lung carcinomas, pheochromocytomas, chemodectomas, and Merkel cell carcinomas. Some of these tumors are functional, while others are non-functional. The signs of disease in dogs and cats depend on the type of growth, location of the tumor, its size, the degree of infiltration in the surrounding tissues, whether it has metastasized, and whether it is functional. A definitive diagnosis requires tissue biopsy and histopathology, often with histochemical staining and electron microscopy. Staging is highly recommended for these tumors. Treatment may involve surgery, chemotherapy, radiation therapy, and medical and dietary management.

• Newfoundland

  Newfoundlands are easygoing, face-washing people lovers and a great choice for the first-time dog owner who is not afraid of a little drool, a big dog, and a lot of hair.

• Norfolk Terrier

  I will fight him with both paws tied behind my back, I will! Yep, that is a Norfolk all right. Sometimes called a demon in the field, the Norfolk is a terrier through and through, with a feisty, scrappy spirit and plenty of energy for the next great adventure. She may be tiny, but buckle your seatbelts - you are in for a terrier of a good time.